{"id":8144,"date":"2022-03-29T12:34:56","date_gmt":"2022-03-29T12:34:56","guid":{"rendered":"https:\/\/live-cancer-factfinder.pantheonsite.io\/fact-finder-tool\/lieu-phap-thay-the-hormone-hrt\/"},"modified":"2026-10-20T15:41:43","modified_gmt":"2026-10-20T15:41:43","slug":"lieu-phap-thay-the-hormone-hrt","status":"publish","type":"post","link":"https:\/\/cancerfactfinder.org\/vi\/cong-cu-tim-kiem-su-that\/lieu-phap-thay-the-hormone-hrt\/","title":{"rendered":"NH\u1eacN \u0110\u1ecaNH: Li\u1ec7u ph\u00e1p thay th\u1ebf hormone (HRT) g\u00e2y ung th\u01b0"},"content":{"rendered":"\n

Nh\u1eefng \u0111i\u1ec1u b\u1ea1n c\u00f3 th\u1ec3 \u0111\u00e3 nghe<\/h2>\n\n

Ph\u1ee5 n\u1eef s\u1eed d\u1ee5ng li\u1ec7u ph\u00e1p thay th\u1ebf hormone c\u00f3 nguy c\u01a1 m\u1eafc ung th\u01b0 v\u00fa cao h\u01a1n. <\/span><\/p>\n\n

Khoa h\u1ecdc cho ch\u00fang ta bi\u1ebft \u0111i\u1ec1u g\u00ec?<\/h2>\n\n

C\u00f3 nhi\u1ec1u lo\u1ea1i li\u1ec7u ph\u00e1p thay th\u1ebf hormone (HRT) kh\u00e1c nhau, bao g\u1ed3m li\u1ec7u ph\u00e1p ch\u1ec9 s\u1eed d\u1ee5ng estrogen, li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p estrogen + progestin, ho\u1eb7c li\u1ec7u ph\u00e1p thay th\u1ebf hormone sinh h\u1ecdc t\u01b0\u01a1ng \u0111\u1ed3ng.<\/span><\/p>\n\n

Estrogen:<\/b> M\u1eb7c d\u00f9 li\u1ec7u ph\u00e1p thay th\u1ebf hormone ch\u1ec9 b\u1eb1ng estrogen gi\u00fap c\u1ea3i thi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng m\u00e3n kinh v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m nguy c\u01a1 ung th\u01b0 v\u00fa \u1edf nh\u1eefng ng\u01b0\u1eddi kh\u00f4ng c\u00f3 ti\u1ec1n s\u1eed gia \u0111\u00ecnh m\u1eafc ung th\u01b0 v\u00fa, nh\u01b0ng n\u00f3 l\u1ea1i l\u00e0m t\u0103ng nguy c\u01a1 ung th\u01b0 n\u1ed9i m\u1ea1c t\u1eed cung (l\u1edbp l\u00f3t c\u1ee7a t\u1eed cung) (<\/span> ACS<\/span><\/a> ). Nguy c\u01a1 ung th\u01b0 n\u1ed9i m\u1ea1c t\u1eed cung v\u1eabn cao h\u01a1n b\u00ecnh th\u01b0\u1eddng ngay c\u1ea3 sau khi ng\u1eebng \u0111i\u1ec1u tr\u1ecb.<\/span><\/p>\n\n

Estrogen + progestin (k\u1ebft h\u1ee3p)<\/b> B\u1ea1n c\u0169ng c\u00f3 th\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c tri\u1ec7u ch\u1ee9ng m\u00e3n kinh b\u1eb1ng li\u1ec7u ph\u00e1p estrogen v\u00e0 progestin, \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 li\u1ec7u ph\u00e1p hormone k\u1ebft h\u1ee3p. Th\u1eddi gian s\u1eed d\u1ee5ng HRT c\u00e0ng l\u00e2u, nguy c\u01a1 c\u00e0ng cao. Nguy c\u01a1 s\u1ebd tr\u1edf l\u1ea1i b\u00ecnh th\u01b0\u1eddng trong v\u00f2ng ba n\u0103m sau khi ng\u1eebng s\u1eed d\u1ee5ng hormone, v\u00ec v\u1eady vi\u1ec7c ng\u1eebng HRT s\u1ebd c\u00f3 l\u1ee3i n\u1ebfu ph\u1ee5 n\u1eef \u0111\u00e3 b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb.<\/span> <\/p>\n\n

Li\u1ec7u ph\u00e1p hormone sinh h\u1ecdc t\u01b0\u01a1ng \u0111\u1ed3ng:<\/b> Li\u1ec7u ph\u00e1p hormone n\u00e0y s\u1eed d\u1ee5ng c\u00e1c hormone ch\u1ee9a estrogen v\u00e0 progesterone c\u00f3 c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc gi\u1ed1ng h\u1ec7t nh\u01b0 c\u00e1c hormone c\u00f3 s\u1eb5n trong c\u01a1 th\u1ec3.<\/span> <\/p>\n\n

B\u1eb1ng ch\u1ee9ng d\u1ecbch t\u1ec5 h\u1ecdc<\/h3>\n\n

Progestin trong li\u1ec7u ph\u00e1p hormone k\u1ebft h\u1ee3p l\u00e0m gi\u1ea3m nguy c\u01a1 ung th\u01b0 n\u1ed9i m\u1ea1c t\u1eed cung do estrogen g\u00e2y ra. Tuy nhi\u00ean, nghi\u00ean c\u1ee9u S\u00e1ng ki\u1ebfn \u200b\u200bS\u1ee9c kh\u1ecfe Ph\u1ee5 n\u1eef (Women’s Health Initiative) cho th\u1ea5y ph\u1ee5 n\u1eef s\u1eed d\u1ee5ng li\u1ec7u ph\u00e1p hormone k\u1ebft h\u1ee3p c\u00f3 nguy c\u01a1 m\u1eafc ung th\u01b0 v\u00fa v\u00e0 ung th\u01b0 bu\u1ed3ng tr\u1ee9ng cao h\u01a1n (<\/span> NCI<\/span><\/a> ). Nghi\u00ean c\u1ee9u Tri\u1ec7u Ph\u1ee5 n\u1eef (Million Women Study) c\u0169ng cho th\u1ea5y s\u1ef1 gia t\u0103ng nguy c\u01a1 ung th\u01b0 v\u00fa \u0111\u1ed1i v\u1edbi li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p estrogen v\u00e0 progestin (<\/span> Clarkson v\u00e0 c\u1ed9ng s\u1ef1<\/span><\/a> ).<\/span><\/p>\n\n

M\u1eb7c d\u00f9 li\u1ec7u ph\u00e1p hormone sinh h\u1ecdc \u0111\u01b0\u1ee3c qu\u1ea3ng c\u00e1o l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn an to\u00e0n h\u01a1n, nh\u01b0ng ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u n\u00e0o ch\u1ee9ng minh r\u1eb1ng ph\u1ee5 n\u1eef s\u1eed d\u1ee5ng hormone sinh h\u1ecdc c\u00f3 \u00edt t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng h\u01a1n (<\/span> NCI<\/span><\/a> ). Hormone sinh h\u1ecdc c\u0169ng ti\u1ec1m \u1ea9n nh\u1eefng r\u1ee7i ro s\u1ee9c kh\u1ecfe t\u01b0\u01a1ng t\u1ef1 nh\u01b0 b\u1ea5t k\u1ef3 lo\u1ea1i li\u1ec7u ph\u00e1p hormone n\u00e0o kh\u00e1c.<\/span><\/p>\n\n

B\u1eb1ng ch\u1ee9ng \u0111\u1ed9c ch\u1ea5t h\u1ecdc\/B\u1eb1ng ch\u1ee9ng h\u1ed7 tr\u1ee3<\/h3>\n\n

C\u00e1c nghi\u00ean c\u1ee9u \u0111\u00e3 xem x\u00e9t t\u00e1c \u0111\u1ed9ng c\u1ee7a li\u1ec7u ph\u00e1p hormone thay th\u1ebf (HRT) tr\u00ean kh\u1ec9 v\u00e0 chu\u1ed9t cho th\u1ea5y vi\u1ec7c s\u1eed d\u1ee5ng estrogen + progestin l\u00e0m t\u0103ng nguy c\u01a1 ung th\u01b0 v\u00fa (<\/span> Clarkson v\u00e0 c\u1ed9ng s\u1ef1<\/span><\/a> )<\/span> .<\/p>\n\n

Ph\u00e2n lo\u1ea1i ch\u1ea5t g\u00e2y ung th\u01b0 c\u1ee7a IARC: <\/span><\/h3>\n\n

Nh\u00f3m 1 (g\u00e2y ung th\u01b0 cho ng\u01b0\u1eddi)<\/span><\/p>\n\n

C\u00e1ch gi\u1ea3m thi\u1ec3u r\u1ee7i ro c\u1ee7a b\u1ea1n<\/h2>\n\n

B\u1ea5t k\u1ef3 quy\u1ebft \u0111\u1ecbnh n\u00e0o v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng estrogen, d\u00f9 d\u00f9ng ri\u00eang l\u1ebb hay k\u1ebft h\u1ee3p v\u1edbi li\u1ec7u ph\u00e1p progestin, \u0111\u1ec1u n\u00ean \u0111\u01b0\u1ee3c \u0111\u01b0a ra b\u1edfi m\u1ed7i ph\u1ee5 n\u1eef v\u00e0 b\u00e1c s\u0129 c\u1ee7a h\u1ecd sau khi c\u00e2n nh\u1eafc r\u1ee7i ro v\u00e0 l\u1ee3i \u00edch (<\/span> ACS<\/span><\/a> ). M\u1ed9t s\u1ed1 \u0111i\u1ec1u c\u1ea7n xem x\u00e9t l\u00e0 nguy c\u01a1 m\u1eafc ung th\u01b0 v\u00fa, ung th\u01b0 n\u1ed9i m\u1ea1c t\u1eed cung v\u00e0 ung th\u01b0 bu\u1ed3ng tr\u1ee9ng (v\u00e0 \u1ea3nh h\u01b0\u1edfng c\u1ee7a li\u1ec7u ph\u00e1p hormone \u0111\u1ebfn nguy c\u01a1 n\u00e0y); nguy c\u01a1 m\u1eafc c\u00e1c b\u1ec7nh l\u00fd nghi\u00eam tr\u1ecdng kh\u00e1c do li\u1ec7u ph\u00e1p hormone g\u00e2y ra (v\u00ed d\u1ee5: b\u1ec7nh tim, \u0111\u1ed9t qu\u1ef5, c\u1ee5c m\u00e1u \u0111\u00f4ng nghi\u00eam tr\u1ecdng v\u00e0 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn n\u00e3o); v\u00e0 c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0o kh\u00e1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng ho\u1eb7c c\u00e1c tri\u1ec7u ch\u1ee9ng m\u00e3n kinh. N\u1ebfu quy\u1ebft \u0111\u1ecbnh s\u1eed d\u1ee5ng li\u1ec7u ph\u00e1p hormone thay th\u1ebf (HRT), t\u1ed1t nh\u1ea5t n\u00ean s\u1eed d\u1ee5ng \u1edf li\u1ec1u th\u1ea5p nh\u1ea5t c\u00f3 th\u1ec3, trong th\u1eddi gian ng\u1eafn nh\u1ea5t v\u00e0 ti\u1ebfp t\u1ee5c kh\u00e1m b\u00e1c s\u0129 th\u01b0\u1eddng xuy\u00ean \u0111\u1ec3 \u0111\u01b0\u1ee3c theo d\u00f5i c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 (<\/span> ACS<\/span><\/a> ).<\/span><\/p>\n\n

L\u01b0u \u00fd: T\u1ea5t c\u1ea3 ph\u1ee5 n\u1eef n\u00ean b\u00e1o c\u00e1o ngay l\u1eadp t\u1ee9c n\u1ebfu c\u00f3 b\u1ea5t k\u1ef3 hi\u1ec7n t\u01b0\u1ee3ng ch\u1ea3y m\u00e1u \u00e2m \u0111\u1ea1o n\u00e0o x\u1ea3y ra sau m\u00e3n kinh; \u0111\u00f3 c\u00f3 th\u1ec3 l\u00e0 d\u1ea5u hi\u1ec7u c\u1ee7a ung th\u01b0 n\u1ed9i m\u1ea1c t\u1eed cung. Ngay c\u1ea3 khi nguy c\u01a1 c\u1ee7a b\u1ea1n kh\u00f4ng cao, b\u1ea1n v\u1eabn c\u00f3 kh\u1ea3 n\u0103ng m\u1eafc ung th\u01b0 n\u1ed9i m\u1ea1c t\u1eed cung. <\/span><\/p>\n\n

T\u00f3m l\u1ea1i<\/h2>\n\n

Li\u1ec7u ph\u00e1p hormone thay th\u1ebf (HRT) c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 m\u1eafc ung th\u01b0 v\u00fa, ung th\u01b0 n\u1ed9i m\u1ea1c t\u1eed cung v\u00e0\/ho\u1eb7c ung th\u01b0 bu\u1ed3ng tr\u1ee9ng. H\u00e3y trao \u0111\u1ed5i v\u1edbi b\u00e1c s\u0129 tr\u01b0\u1edbc khi quy\u1ebft \u0111\u1ecbnh v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng li\u1ec7u ph\u00e1p hormone thay th\u1ebf. <\/p>\n","protected":false},"excerpt":{"rendered":"

Nh\u1eefng \u0111i\u1ec1u b\u1ea1n c\u00f3 th\u1ec3 \u0111\u00e3 nghe Ph\u1ee5 n\u1eef s\u1eed d\u1ee5ng li\u1ec7u ph\u00e1p thay th\u1ebf hormone c\u00f3 nguy c\u01a1 m\u1eafc ung th\u01b0 v\u00fa cao h\u01a1n. Khoa h\u1ecdc cho ch\u00fang ta bi\u1ebft \u0111i\u1ec1u g\u00ec? C\u00f3 nhi\u1ec1u lo\u1ea1i li\u1ec7u ph\u00e1p thay th\u1ebf hormone (HRT) kh\u00e1c nhau, bao g\u1ed3m li\u1ec7u ph\u00e1p ch\u1ec9 s\u1eed d\u1ee5ng estrogen, li\u1ec7u ph\u00e1p k\u1ebft…<\/p>\n","protected":false},"author":1,"featured_media":8146,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[557],"tags":[523],"class_list":["post-8144","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-van-de-hoac-dieu-tri-y-te","tag-chac-chan-hoac-rat-co-the-la-dung"],"acf":[],"_links":{"self":[{"href":"https:\/\/cancerfactfinder.org\/vi\/wp-json\/wp\/v2\/posts\/8144","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cancerfactfinder.org\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cancerfactfinder.org\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cancerfactfinder.org\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cancerfactfinder.org\/vi\/wp-json\/wp\/v2\/comments?post=8144"}],"version-history":[{"count":10,"href":"https:\/\/cancerfactfinder.org\/vi\/wp-json\/wp\/v2\/posts\/8144\/revisions"}],"predecessor-version":[{"id":17290,"href":"https:\/\/cancerfactfinder.org\/vi\/wp-json\/wp\/v2\/posts\/8144\/revisions\/17290"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cancerfactfinder.org\/vi\/wp-json\/wp\/v2\/media\/8146"}],"wp:attachment":[{"href":"https:\/\/cancerfactfinder.org\/vi\/wp-json\/wp\/v2\/media?parent=8144"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cancerfactfinder.org\/vi\/wp-json\/wp\/v2\/categories?post=8144"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cancerfactfinder.org\/vi\/wp-json\/wp\/v2\/tags?post=8144"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}